By Alfred J. Plechner, D.V.M.

The history of hormone therapy has been less than satisfactory, in trying to provide hormone replacement. Have you ever asked yourself, why this has not worked for you or your pet? Did you ever think that the medical profession has no idea either? We base our, hopefully, educated suggestions, on clinical signs and symptoms. There is an overpowering feeling, by the heath care professionals, that to depend on those empirical results, from various laboratories, may not help with the diagnosis. When I had the opportunity to speak to the Broda Barnes MD foundation, all the health care professionals agreed that, the blood tests that they had sent into various labs, could not be, believed. The question for you to ask, is why not?

Twenty-four hour urine tests were done to identify active cortisol, even though, cortisol serum tests were not done, because many of the health care professionals were not allowed to do blood tests. You need to do both, to determine if the measured cortisol level is even working. I did a metabolic cage, 38 years ago, to collect a 24 urine sample from my patients, and then compared their urine and serum levels, to see if the patient actually had active, working levels of cortisol. I did find that even if they had adequate measurable levels of cortisol, it was not working. Salivary tests were created, not only for the identification of an active cortisol, but also because these health care professionals were not allowed to draw blood and do the comparison. Their protocol called for doing early morning cortisols and often continuing doing four hour levels later because they were looking at not only a Sarcadium Rhythem between the pituitary gland and the middle layer adrenal cortex, but also trying to base their diagnosis and therapy upon these measured levels. How, do they know these are active levels? They do not, but yet they will prescribe and treat, and help you become a statistic instead of a success story.

The only way you can really know what is active and inactive is by doing the Atypical Cortisol Estrogen Imbalance Syndrome (ACEIS) or as the public refers to it as Plechner’s Syndrome, which is comparative and not empirical. Remember, it is not the amount of hormone you may have, it is whether it is working or not. Your Immune antibody production will tell you this. The tests are available today, in most labs, but heir tests are either incomplete, or do not have qualified people to these tests accurately. As things stand, their tests not identify your problem and my syndrome. Please check my website for proper laboratory input.

Additional Information

Safe Uses of Cortisol

William McK. Jefferies, MD

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